Is it safe to take fexofenadine for a long time? Fexofenadine is unlikely to do you any harm if you take it for a long time. But it's best to take fexofenadine only for as long as you need to.
Hepatotoxicity. Fexofenadine use is not generally associated with liver enzyme elevations but terfenadine, a second generation antihistamine that is metabolized in part to fexofenadine, was the attributed cause of several reported cases of clinically apparent liver injury.
Fexofenadine hydrochloride pharmacokinetics are linear for oral doses up to a total daily dose of 240 mg (120 mg twice daily).
In general, fexofenadine takes about one hour to take effect, though this may be affected by the choice of dosage form and the presence/absence of certain foods.
One trial reported that fexofenadine was superior to loratadine with regards to wheal and flare suppression (allergic skin reaction), with a faster onset of effect and a more effective suppression of the flare at each time point in the study (Kaliner et al).
Avoid taking an antacid within 2 hours before or after you take fexofenadine. Certain antacids can make it harder for your body to absorb this medicine. Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.
For allergy sufferers with heart disease, medicines such as Allegra, Zyrtec or Claritin should be safe. However, medicines containing decongestants — including Allegra-D, Zyrtec-D and Claritin-D — could increase your blood pressure and heart rate or interfere with your heart medication.
Fexofenadine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.
Fexofenadine, even in dosages exceeding those recommended, is the least sedating of all second-generation antihistamines and is considered the antihistamine of choice for people in safety-critical jobs such as airline pilots. Can be taken once a day.
The recommended dose is one tablet (180 mg) daily. Take your tablet with water before a meal. This medicine starts to relieve your symptoms within 1 hour and lasts for 24 hours.